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CPC On-Demand Webinars

01 Jul 2020

Clinical Trials searching for treatments for COVID-19

On Wednesday 17th June, Kathryn Murray, Lead Clinical Trials Pharmacist, Cardiff and Vale University Health Board, discussed potential COVID-19 treatments, introducing the clinical trials taking place in the UK to test these treatments and the challenges that face setting up trials in a pandemic. Kathryn touched on these potential treatments and proceeded to discuss:

  • The Background of the COVID-19 pandemic
    • Virology – identifying COVID-19, previous Coronavirus outbreaks and relation to SAR-CoV2
    • Signs and symptoms – European Hospital Data and New York data
    • Risk factors for severe disease – disparities in the risk and outcomes (age, sex, geography, ethnicity etc.)
    • Complement activation – progression of COVID-19
  • Clinical Trials Exploring Potential Treatments
    • Corticosteroids
    • Anti-viral – Remdesivir, Hydroxychloroquine, Lopinavir/ritonavir, Azithromycin
    • Immune modulation agents – Anakinra, Tocilizumab, Ravulizumab, Canakinumab, Complement C5 Inhibitor
    • Convalescent Plasma
    • Recovery - randomisation
  • Challenges to setting up trials during COVID-19
    • Speed of trial set up
    • Availability of drug treatment
    • Drug preparation at ward level
    • Immune suppression

Register and watch on-demand here: https://www.pharmacycongress.co.uk/live-webinar-or-on-demand#/

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