• A review of pharmacotherapy options for chronic insomnia, looking at:
  • Drug classes
  • Clinical pharmacology
• Describe the role of orexin in the sleep/wake cycle.
• Examine the evidence for targeting over-active wakefulness in the treatment of chronic insomnia.
• Review NICE Clinical Knowledge Summary on Insomnia, plus relevant NICE guidance on:
  • Benzodiazepines & Z-drugs
  • PR melatonin
  • Orexin receptor antagonist 

This promotional presentation has been funded by Idorsia Pharmaceuticals UK Ltd and is intended for UK healthcare professionals only. Idorsia products will be discussed in this session.

UK-DA-01434 | Date of prep: March 2026