In April 2026 amendments were made to the Human Medicines Regulations 2012 to support the ongoing supply and deployment of vaccinations across the UK.  These changes are significant in improving vaccination access and models of delivery building on learning from the pandemic. Changes include a new legal mechanism for vaccination administration (a Vaccine Group Direction), access to NHS vaccinations via community pharmacies and changes to the Occupational Health Vaccinator role.  This session will outline the amendments and their implications for practice and vaccination delivery.