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Penicillin allergy de-labelling – rationale, supporting resources and potential role of pharmacists’

13 May 2022

Around 10% of people have a documented allergy to penicillin but the rate of true allergy is only 1-2%. The impact of having an allergy limits the choice of antibiotics that can be given with potential adverse consequences in terms of effective treatment, resistant organisms and side effects. In Scotland, a national project developed and tested a toolkit to remove penicillin allergy labels from patients at low risk of true allergy. The project results were encouraging and there was positive feedback from clinicians and patients. Published evidence supports the role of pharmacists in de-labelling processes and various resources are under development to enable a standardised approach including education to ensure de-labelling is safe for implementation by non allergy specialists. Technology may offer solutions to the current barriers around robust de-labelling processes.


Learning outcomes:

To understand the importance of accurate penicillin allergy status
To discuss use of a national toolkit to support penicillin allergy de-labelling in patients at low risk of true allergy
To understand how pharmacists can support penicillin allergy de-labelling
To raise awareness of resources to support de-labelling and how technology can facilitate the process


Dr Jacqueline Sneddon, programmes manager - British Society for Antimicrobial Chemotherapy


Lead Education Partner

  • CPPE
  • Morph


Education Partner

  • BOPA
  • BPNG
  • CMHP
  • Health Education England


Education Partner

  • NHS England and NHS Improvement
  • NHS Digital
  • NHSx
  • PTOC
  • GPHC


Education Partner

  • NPPG
  • PCPA
  • PDA
  • Pharmacist Support
  • RPUK
  • SPS


Education Partner

  • Soar Beyond
  • NHCA
  • PrescQIPP
  • Pharmacy Declares
  • GHP and RPS


Media Partner

  • C&D
  • PDA
  • PrescQIPP
  • Scottish Healthcare Review
  • Welsh Healthcare Review
  • NI Healthcare Review
  • Prescriber


Nominated Charity

  • Pharmacist Support


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